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KMID : 1155520170120030243
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Anesthesia and Pain Medicine
2017 Volume.12 No. 3 p.243 ~ p.246
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Anesthetic management of a patient with glucose-6-phosphate dehydrogenase deficiency undergoing robot-assisted laparoscopic surgery -A case report-
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Cho Ha-Na
Lee Seung-Young
Kim Gunn-Hee
Kim Ji-Eun
Koo Min-Seok
Yun Mi-Jung
Kwon Mi-Young
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Abstract
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The authors describe the successful perioperative management of a 3-year-old boy from Dubai with glucose-6-phosphate dehydrogenase (G6PD) deficiency, who underwent robot-assisted laparoscopic pyeloplasty for complete right ureteropelvic junction obstruction. G6PD deficiency is a genetic disorder predisposing patients to hemolytic anemia from oxidative stress. Important considerations in anesthetic management include avoiding oxidative stress, which can be caused by various conditions, and monitoring for hypercapnia, which can cause acidosis and hemolysis. Laparoscopic surgery is usually associated with hypercapnia and therefore an increased risk for respiratory acidosis. During surgery in this particular case, efforts were made to avoid carbon dioxide retention and to keep the patient warm. General anesthesia was induced with thiopental sodium, rocuronium, and fentanyl, and maintained with sevoflurane. There were no signs of hemolysis in the perioperative period and he was discharged owing to his improved condition.
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KEYWORD
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Glucose-6-phosphate dehydrogenase deficiency, Respiratory acidosis
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